Creating Cajun Cream Cheese Chicken Pasta Bake is simple if you follow these straightforward steps:

1. Preheat Oven: Begin by preheating your oven to 350°F (175°C).
2. Cook Pasta: In a large pot, boil water and cook pasta according to package instructions. Drain and set aside.
3. Sauté Chicken: In a large skillet, heat the olive oil over medium heat. Add the diced chicken and season with Cajun seasoning, garlic powder, onion powder, salt, and pepper. Cook until the chicken is browned and cooked through, about 5-7 minutes.
4. Prepare Cheese Sauce: In a large mixing bowl, combine the softened cream cheese and chicken broth. Use a whisk or fork to blend until smooth.
5. Combine Ingredients: Add the cooked pasta and sautéed chicken to the cheese mixture. Stir in the cheddar and mozzarella cheese until everything is well combined.
6. Transfer to Casserole Dish: Grease a 9×13 inch casserole dish. Pour the chicken and pasta mixture into the dish, spreading it evenly.
7. Bake: Place the casserole in the preheated oven for 25-30 minutes, or until the cheese is melted and bubbly.
8. Cool and Garnish: Once baked, remove from the oven and let it cool for 5-10 minutes. Garnish with chopped green onions if using.

Following these steps will guide you in creating this incredible dish effortlessly.